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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b262dd5cc8036f2078be31da9706cd067a545ff095dde3aebe4293a837fc3b' 
  AND token = 'y9oUhSPgx6jBT0i6xlalRY30PelpgOCGKY2QQuvQf6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}