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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91173490d3d55f95bac111996543acb321d9359345bc391e26d6ee800f0188c3' 
  AND token = 't1DZnIuVduGgsuLFzxT4ZXfP3hUt40d4/RRPlmJFd6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}