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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff5c9f35ff82bfc13c1187bc3e2b03cb1e048f34a5e212293c926c1ceaf0b157' 
  AND token = 'YcAermB2CynPy0oL8Kjpf6GJOdj39wb7x4Ait4PAHak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}