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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad1e10bd0e877d6fccaf2b37b9f428d9d1e185f1c24ce089104c909cea76890' 
  AND token = 'RmnD3CJA8+M5RlsLjeHgvbW2MkSjOidV+cdvHFQNGE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}