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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd20fd1b88dbee2589cf06c35aa045ba6cf807757be6653735ad60b56dc1461a6' 
  AND token = 'noOfK8PTkg3Ov2X2VcHHZjxNKG8fLOHDkw5b1DED4Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}