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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11293a23c48f15a3ff2b1da8df35903745ed100dc2e7e2c721f5e5131b9602cd' 
  AND token = 'V9LnDnnEF0kd/8J/A4dZiH9Rm1uHyIaeCyov2V/MSyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}