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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b18de401b56c2a07e069cd027a891480ed771a3638592d22f8f855cb57cf76d' 
  AND token = 'D/D++z/KOidnfXnE64Mvt2ZTQ3Myv7W15NZ9zBzi+hY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}