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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76b57fb8c049f3ab3084414b8f6b9910ad36ca01adeff56703c02ea8a5070528' 
  AND token = 'ZbmPtYyCGkyEb30rlChdloffI4jb+s/WKN7p3mZ4QfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}