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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c2120caa3eaeabce227c4bc9de13cab86cd45d8248a12b3555486eb00a0a5a' 
  AND token = 'Off8T5AU6AUMQGOOwpyELhzqQtfdiQwspOusvK54pjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}