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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c454ae011239352edf4de3e1e6733053b0731bbe82dfd081c6240dccf7229216' 
  AND token = 'uzEVfMqtBGrES5sutjyLe+m1vUcmK+JGCqsqrxfcAnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}