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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25da6e5c27fb12468066cd8afe3a09170e0ec654ae5fd353f074f9123c84456d' 
  AND token = 'tmfkjnwPkPgk0eN2RLKjB133T0dWHTyUuli8CVoUL50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}