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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1591574538aa424426b54f11f0cfdcfa88853fb663ef6c2bea57576a3160ddd' 
  AND token = 'fJK8RldL1QyIOSli+PW2PrpX/pUdVpq46L5UqGMqs0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}