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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d05a7216bdcc7a04fd374e4aee4c1f0bfd0478814ab8803793629009c72e12b' 
  AND token = 'JjmcE9unQWR8YniMwA3Kiyi0sX6pMXPIQMI0d27szPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}