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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c286003caf8939d6e2500933a2a9fc3717b5c2d9c169cde4fc570722371e3066' 
  AND token = 'TOZ7zo9ceBW6LIpNlRN6Qa06SBERO/KzBZCMI6fN7D0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}