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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f9b5a4db82a7166b5e5031bb58a29491e4665fa48dba8b4fb56749739b8f051' 
  AND token = '9+nZ4HdKbbszbEr6/W4WABQ8AwRMQqpz40J2XLrp0Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}