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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0951fa0e3001cd123f3a0dd93a812e760db3478e03f0fd1891d982238ba3dfdc' 
  AND token = 'CzA8STFviwe9sDxB1WwlkuvxvsbPJoZxeA+D2vIEdx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}