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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fef1a55d27991d17c21d1297cf71e9a99b3332b0cdff4a96fc4a7e71541eb12' 
  AND token = '1fRb22XZIwwT3DHY92pHmsGJ4fsOGF7RQjWgvUoOzRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}