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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c43ee74928c3ad9cec5a44d6146ac17723bc66f96061facc0d8bffcbfd2de61' 
  AND token = 'fOBp3KgfSza70cJ1NUp/1yP/UJjOG4KWOZ8tWxLMAoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}