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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a50907736b7f0769630b19e0777eef5b8f447c80234766e532bcd38566bd37c5' 
  AND token = 'z9Iy0Z5wFk/irg73u3oWx23PtUtSxaI96+hMBnrvGDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}