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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ddc77cc2707d35feb2fdb5a4579f947df2391810595f5641b236caf624b7a6' 
  AND token = 'voUKowMpkXuHOCOf4PaXLvpN6sF5HlcvbpUaEp+35yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}