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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e143b4400aa297aadcff8e08481d6d5d0b2899bcbe9149bf7e225f29acf9ffcd' 
  AND token = 'drFRk+Mfs2c1P83iEQf5hcgAnlVeDG23oBVzm9qoKTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}