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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241af0c5d75d32434b76d70ddf443c2500384eb8141341e535aad29904d9caef' 
  AND token = 'qVXHaaEGCE7Iq/xZqB+M/Gt9ab0ROghFoVwhV1/3qGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}