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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed21b0f90980fe07a74919091f61b9801646de25a47d474181793b4e80e4c03e' 
  AND token = 'mBhr68RXzfgMii/W5pJUgg6iIKT9U22GP0rWRth/fds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}