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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf089806ac0146c1273cf51cd4f050d117152dbfb73c0f11826cbdec742af514' 
  AND token = 'QhV2TJXHHK4oXERwjX8ucbCZeYt3raSGdIRuCE2wS5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}