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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf49ca6b751ac1dfd186769ab016e64e7a801584f4fdcef4b6eacb7bb87069be' 
  AND token = 'wPqMMpzhgV7ej6oMShHX3TetJWnXaYshpFtfwRTkUOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}