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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca80729f7f3eb7b87331ab233f06b9d85552c8c158955d8b36f9a7bb296ae26' 
  AND token = 'hseSxwbOZotMgyTWBKYSQ7oc7jgHaA9SQ+72W/WEnHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}