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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779d1873d991d91c7ef1cbd8b3b85d2bfa552579cee8ee9b0b25a259ebd2f1dc' 
  AND token = 'U8uUPtAXJEAv7icZJbG8Iov/Lj5T9kP5La3ajEbx7Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}