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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196d193645013c002e0676b7ae78d1752b5affb22860c38bb3e58b6063623b03' 
  AND token = 'bKEs8fIu9zB/OACBvxst3VxwbkbW9RQDE8PiG/5aYTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}