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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42351e03fd197ef45a2fac4e02deb33eae9e52c1d354985aeac9ca32e7123ef5' 
  AND token = '/h6kJ+M/Zz/MbvazQJcMlyILHEkryDMf3Bo0T/HuaU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}