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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ec7a0c28d09ea5f335f1010a4d467a576a33933938f2feb3ce0f474468f682' 
  AND token = 'Zkm7MXlBXKDEjO63ZLD6KnE9bIceoF7Ik1BDCvXb48k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}