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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ccecbae0c60f7a42098c40b94a0c072a43153aece3fe2b63e1fbb8243e5c10e' 
  AND token = '1yjOvIxUJHD5qJg6+zlkaxCzBZfUPoQIOKLZWP6RDlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}