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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d75f0e1c8ffddb41e073fe7d5c2748c6faaebbb1ecaf35f99544f6f51369c0' 
  AND token = 'QSvc1yZbkyjTe8obl4ua1LKv3Sm4hk6G65DEjbio2Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}