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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3d2d12e8c827bb8174f59ce3df28e87e70bff4af5a8b97279c0d2c79c5826b' 
  AND token = 'LxfbyTY52bujzrW34/1OuMW+2fqTCIhcxNGK5Y8x/W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}