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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604601e0b238961af01a34b1551c85b58a44da0c97f3095b509c60d50d2292f1' 
  AND token = 'ySgsmHlLHTZsIWSnNN09sZqvJO5gHh61NHm8fs/cEwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}