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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '010e081e72116f50251b93824fceb2054bdebfb34f04563853135499b48e6c8c' 
  AND token = 'B8RaQBiNGj33VycXVQoshu4SOyOOwoNHzr6sgzVP7gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}