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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216bd79778ecc0149b8d7be96e1ed6d9f57410d42dc729ad4721dbeef9235fa9' 
  AND token = 'L4I0kOui54hArd896tKqF0PATSg3zXctbAIjsEWxMBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}