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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b7db357a7cd2cd6d00aebe0fec345251d073fda31d33b203b0bf88220b5c1c' 
  AND token = 'h2Hmd7VTzazorPyvCtk2rNE/8mn5lye4rTVjoCpsLfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}