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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2edbd59a306bc5affa8e05e3b73ffb5dbced15ea819a9012f0aced8cb9aff9f1' 
  AND token = 'OI3k1ZQ8guCkJ7hutsQWqV5+rxJzVNbKktPEH7AY+AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}