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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5cef20eb5da4936babfe00fbb26fa1c47c4a8ceb68c03ef2aa50f71293d325' 
  AND token = '/s7+YXh6FlcZJRxDh0h9XkuZ38Jysxp32ATxLHjrSuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}