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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec6aa6afb0be5ba5b0d419e52acbdcdfa5352eeaafa9d2214e1d49dc5faa58c' 
  AND token = 'ROkOlLj4EOT2NclXV1K9H3HEEm7gN4LrIrPDCPqgzL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}