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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8ac7ef5306df39c80e31dbf9fc78f98bf288df7873d55457ecbcfe8ad81ed6' 
  AND token = 'ISKBHaOymf+hb1zxrX51TFccqSoAcvnS3j2jTMw3GEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}