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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8817fbe3424545dca9d45f09fa0f9fb7b03b82f4127c9d855b0e225d22b4ce7' 
  AND token = '2XkE2RPMPwG3ehM0z76tmtDsGrxHo62+LpqSx8oTMF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}