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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086befe018146c1d7cd3b46b1c84bc0dd4055ceabc3b30e8946f99f7f4da995e' 
  AND token = 'E5OlolbOL4HlhTjazCeF0rc+Ao3Jnldo5IKVp4htWj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}