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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d6187041733a3c0176bdccac05b0f574f9db1a8fe5f51650c37c1dd4fdf3676' 
  AND token = 'D9kgh+YbZGL/k9K4n6sru7tDPSDSjCNmbM/Jf8Bbiu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}