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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd56b5359d43235c6aba660fce5b64303e14539aaf283a3b65182dcc14fdb5340' 
  AND token = 'YUT46+P4NJloNKMuygOJzOZ24AOBd3Dk0dRVcJhdAUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}