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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c774d0932bcbebbb52a04726de63b337025cd87f7e6dcf6ed30e729b77e15f' 
  AND token = '+IR9AvYL5RMF6Zkmpm1IufLHUb9ZMZCigwTNaBieKo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}