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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c8803d3db4f3d82370c353394b52a4dd256e16fd8fc3aa61c241696e1ee192' 
  AND token = 'rSlsWaCLKtH+GfGPLQBGwOKen4xCVsafTNpdDc0T2DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}