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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2a1da91222086b32974b6095c030a597cc4f33d2dfdfea375d21dd14e3c31b' 
  AND token = 'e65HWyrAq5x/UO7PpwdPzgtNidMPWqtfiN83pSufaAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}