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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c7c9a3d6473665a223a0f41707ad406e4469a92ed44dddeb8a0def01e2e075' 
  AND token = 'zzks7CF84i0xhvSdW0O5VGhT5FiuacmkyC0GlVI4Ddo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}