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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc3cb246c77b52d2e5f5e316e6f7d842d5ef281d8d32d24fe04473943ce598f3' 
  AND token = '++pO2ndaEpZLVcIWkb7uDYGALpACnyw7T3Zl3hV2MV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}